'Body on a chip' promises improved drug evaluation: Page 3 of 3

March 14, 2018 //By Rich Pell
'Body on a chip' promises improved drug evaluation
Engineers at MIT (Cambridge, MA) say they have developed new technology that could be used to evaluate new drugs and detect possible side effects before the drugs are tested in humans.
enter the bloodstream and produce inflammation in the liver.

The researchers see the most immediate applications for this technology as involving the modeling of two to four organs, and are are now developing a model system for Parkinson's disease that includes brain, liver, and gastrointestinal tissue. Other applications, says Griffith, include modeling tumors that metastasize to other parts of the body.

"An advantage of our platform is that we can scale it up or down and accommodate a lot of different configurations," Griffith says. "I think the field is going to go through a transition where we start to get more information out of a three-organ or four-organ system, and it will start to become cost-competitive because the information you’re getting is so much more valuable."

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